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Key Documents

850320C

Avanti

09:0 PC

1,2-dinonanoyl-sn-glycero-3-phosphocholine, chloroform

Sinônimo(s):

PC(9:0/9:0)

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About This Item

Fórmula empírica (Notação de Hill):
C26H52NO8P
Número CAS:
Peso molecular:
537.67
Código UNSPSC:
12352211
NACRES:
NA.25

Ensaio

>99% (TLC)

forma

liquid

embalagem

pkg of 1 × 2.5 mL (850320C-25mg)

fabricante/nome comercial

Avanti Research - A Croda Brand 850320C

concentração

10 mg/mL (850320C-25mg)

tipo de lipídio

cardiolipins
phospholipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

InChI

1S/C26H52NO8P/c1-6-8-10-12-14-16-18-25(28)32-22-24(35-26(29)19-17-15-13-11-9-7-2)23-34-36(30,31)33-21-20-27(3,4)5/h24H,6-23H2,1-5H3/t24-/m1/s1

chave InChI

CKGVBFQDYSPMSY-XMMPIXPASA-N

Descrição geral

Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the membrane. The fatty acids in the sn-1 and sn-2 positions of PCs are covalently attached to a glycerol with the help of ester bonds.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicação

09:0 PC (1,2-dinonanoyl-sn-glycero-3-phosphocholine) may be used:
  • as an internal standard for phospholipid extraction from renal tissues using liquid chromatography coupled to electrospray ionization tandem mass spectrometry
  • as a supplement in sample mixture as internal standard for liquid-liquid extraction and to spike the samples in order to determine lipid extract from fibroblasts by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
  • an internal standard to spike frozen aliquots of plasma in liquid chromatography with tandem mass spectrometry (LC-MS-MS)

Ações bioquímicas/fisiológicas

The physical properties of membranes can be modulated with the help of fatty acyl configuration of phosphatidylcholines (PCs). They serve as a major source for eicosanoids.

Embalagem

5 mL Clear Glass Sealed Ampule (850320C-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órgãos-alvo

Central nervous system

Classe de risco de água (WGK)

WGK 3


Certificados de análise (COA)

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Florian Gruber et al.
Journal of lipid research, 53(6), 1232-1242 (2012-03-15)
Oxidized phospholipids (OxPLs) are increasingly recognized as signaling mediators that are not only markers of oxidative stress but are also "makers" of pathology relevant to disease pathogenesis. Understanding the biological role of individual molecular species of OxPLs requires the knowledge
Zahra Solati et al.
PloS one, 13(4), e0195172-e0195172 (2018-04-24)
The aim of this study was to determine the individual oxidized phosphatidylcholine (OxPC) molecules generated during renal ischemia/ reperfusion (I/R) injury. Kidney ischemia was induced in male Sprague-Dawley rats by clamping the left renal pedicle for 45 min followed by

Artigos

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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