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Key Documents

840044C

Avanti

Soy PI

Avanti Research - A Croda Brand 840044C

Sinônimo(s):

L-α-phosphatidylinositol (Soy) (sodium salt)

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About This Item

Número CAS:
Código UNSPSC:
12352211
NACRES:
NA.25

Ensaio

>99% (TLC)

forma

liquid

embalagem

pkg of 1 × 1 mL (840044C-10mg)
pkg of 1 × 2 mL (840044C-50mg)
pkg of 1 × 2.5 mL (840044C-25mg)

fabricante/nome comercial

Avanti Research - A Croda Brand 840044C

concentração

10 mg/mL (840044C-10mg)
10 mg/mL (840044C-25mg)
25 mg/mL (840044C-50mg)

tipo de lipídio

phosphoglycerides

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP([O-])(OC[C@@]([H])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O.[Na+]

InChI

1S/C43H79O13P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(45)55-35(34-54-57(51,52)56-43-41(49)39(47)38(46)40(48)42(43)50)33-53-36(44)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35,38-43,46-50H,3-10,12,14-16,19-34H2,1-2H3,(H,51,52);/q;+1/p-1/b13-11-,18-17-;/t35-,38?,39-,40?,41?,42?,43-;/m1./s1

chave InChI

DCDQYHYLAGWAPO-UQZYTPKFSA-M

Descrição geral

L-α-phosphatidylinositol (Soy) is a naturally occurring, negatively charged glycerophospholipid with an inositol ring. It is found in biological membranes, which are involved in scaffolding, cellular compartmentalization and signal transduction.

Aplicação

Soy PI has been used in PI 3-kinase assay.

Ações bioquímicas/fisiológicas

L-α-phosphatidylinositol (Soy) acts as a cellular mediator in signal transduction processes. It is used to design therapeutic delivery vehicles for drug delivery. Soy PI also contributes to the regulation of cholesterol metabolism.

Embalagem

5 mL Clear Glass Sealed Ampule (840044C-10mg)
5 mL Clear Glass Sealed Ampule (840044C-25mg)
5 mL Clear Glass Sealed Ampule (840044C-50mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órgãos-alvo

Central nervous system, Liver,Kidney

Código de classe de armazenamento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

does not flash

Ponto de fulgor (°C)

does not flash


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Visite a Biblioteca de Documentos

Vps34 kinase domain dynamics regulate the autophagic PI 3-kinase complex
Stjepanovic G, et al.
Molecular Cell, 67(3), 528-534 (2017)
Aaron Peng et al.
Chemistry and physics of lipids, 165(1), 15-22 (2011-10-26)
Liposomes consisted of phosphatidylinositol (PI) and phosphatidylcholine (PC) have been utilized as delivery vehicle for drugs and proteins. In the present work, we studied the effect of soy PI on physical properties of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes such as phase state
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin
Kimble-Hill, et al.
The Journal of Physical Chemistry B, 122(35), 8404-8415 (2018)
Ashutosh Tripathi et al.
The Journal of biological chemistry, 294(50), 19081-19098 (2019-11-07)
Phosphatidylinositol-transfer proteins (PITPs) are key regulators of lipid signaling in eukaryotic cells. These proteins both potentiate the activities of phosphatidylinositol (PtdIns) 4-OH kinases and help channel production of specific pools of phosphatidylinositol 4-phosphate (PtdIns(4)P) dedicated to specific biological outcomes. In
Phospholipids as cardiovascular therapeutics
Pandey NR and Sparks DL
Current Opinion in Investigational Drugs, 9(3), 281-285 (2008)

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