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T111

Sigma-Aldrich

8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride

≥98%

Sinônimo(s):

TMB 8 hydrochloride, TMB-8 · HCl

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About This Item

Fórmula linear:
(CH3O)3C6H2CO2(CH2)8N(C2H5)2 · HCl
Número CAS:
53464-72-5
Peso molecular:
431.99
Beilstein:
5466611
Número CE:
258-574-5
Número MDL:
MFCD00012502
Código UNSPSC:
12352100
ID de substância PubChem:
57654652
NACRES:
NA.22

Nível de qualidade

100

Ensaio

≥98%

Formulário

powder

pf

94-97 °C (lit.)

cadeia de caracteres SMILES

Cl[H].CCN(CC)CCCCCCCCOC(=O)c1cc(OC)c(OC)c(OC)c1

InChI

1S/C22H37NO5.ClH/c1-6-23(7-2)14-12-10-8-9-11-13-15-28-22(24)18-16-19(25-3)21(27-5)20(17-18)26-4;/h16-17H,6-15H2,1-5H3;1H

chave InChI

KFJZVXKPPQIYCG-UHFFFAOYSA-N

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Aplicação

  • Pharmacologically active inhibitor of hepatitis C virus life cycle

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

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Pierre Poutrain et al.
Journal of experimental botany, 60(4), 1387-1398 (2009-02-17)
Calcium-mediated signalling is ubiquitous in both animals and plants. Changes in cytoplasmic free Ca(2+) concentration couple diverse arrays of stimuli to their specific responses, the specificity of the stimulus being determined by integrated actions between multiple Ca(2+) mobilization pathways. In
Fabián Bernal et al.
Journal of neuroscience research, 87(5), 1240-1249 (2008-11-14)
Human cerebral calcification has been related to deregulation of intracellular calcium homeostasis. In rat basal ganglia, nimodipine and TMB-8, two commonly used calcium antagonists, worsen the chronic AMPA-induced lesion, whereas only nimodipine potentiates calcification. To investigate whether similar effects are
Hiroaki Tosuji et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 147(2), 432-437 (2007-02-24)
During meiosis in oocytes of the starfish, Asterina pectinifera, a Ca(2+) transient has been observed. To clarify the role of Ca(2+) during oocyte maturation in starfish, an intracellular Ca(2+) blocker, TMB-8, was applied. The oocyte maturation induced by 1-methyladenine (1-MA)
Travis J Nickels et al.
Clinical and experimental pharmacology & physiology, 33(5-6), 465-470 (2006-05-17)
1. Theophylline and aminophylline have been widely used as inhibitors of phosphodiesterase when examining the role of cAMP in regulating cell function. In reality, however, these phosphodiesterase inhibitors may have additional sites of action that could complicate the interpretation of
Maria Luisa Zaccardi et al.
Behavioural brain research, 229(1), 235-243 (2012-01-31)
Although habituation is ubiquitous in the animal kingdom, its underlying mechanisms remain poorly understood. In this study, we began to explore the molecular cascades underlying short-term habituation in the leech Hirudo medicinalis. In H. medicinalis, a training paradigm, consisting of
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