Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

933554

Sigma-Aldrich

NanoFabTx™ NTA Lipid Mix

for synthesis of NTA-functionalized liposomes for small molecule delivery

Sinônimo(s):

Cholesterol, DGS-NTA(Ni), HSPC, PEG-DSPE

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Código UNSPSC:
12352211
NACRES:
NA.21

Nível de qualidade

100

temperatura de armazenamento

−20°C

Aplicação

NanoFabTx™ NTA Lipid Mix is a ready-to-use nanoformulation lipid mixture for the synthesis of NTA-functionalized liposomes. This lipid mix enables users to encapsulate a wide variety of small molecules for targeting and immunotherapy applications without the need for lengthy trial-and-error optimization.
This product includes a curated lyophilized lipid mixture containing rationally selected lipids in precise ratios that have been optimized to achieve a desired size range of liposomes. Step-by-step protocols for the synthesis of liposomes surface-functionalized with NTA groups using extrusion and microfluidics are also included. The synthesized NTA-functionalized liposomes enable the conjugation of His-tagged antibodies or proteins to the liposomes surface for immunothereapy applications and multi-targeting or multi-type cargo delivery.

Características e benefícios

  • A ready-to-use nanoformulation lipid blend for the synthesis of NTA-functionalized liposomes
  • Step-by-step extrusion and microfluidics protocols for liposome synthesis developed and tested by our formulation scientists
  • Flexible synthesis methods to create uniform and reproducible liposomes
  • Protocols and lipid blend optimized to make liposomes around 100 nm diameter with low polydispersity
  • Lipid mix optimized for His-tagged protein or antibody conjugation and small molecule encapsulation
Comprehensive protocols for liposome synthesis are included:
  • A lipid film hydration and extrusion protocol
  • A microfluidics protocol using commercial platforms or syringe pumps
The microfluidics protocol included with this product uses the NanoFabTx™ device kit (911593). These kits come with the microfluidics chips, fittings, and tubing required to get started with microfluidics-based synthesis (compatible microfluidics system or syringe pump required).

Informações legais

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Se precisar de ajuda, entre em contato Atendimento ao cliente

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Mesoscale active matter in fluids
Klotsa, Daphne
Soft Matter (2019)

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica