909858
Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide)
PEG average Mn 5,000, PLGA average Mn 20,000, lactide:glycolide 50:50
Sinônimo(s):
COOH-PEG-PLGA, Carboxylic acid PEG-PLGA
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About This Item
Fórmula linear:
H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nC2H3O2
Código UNSPSC:
12352106
NACRES:
NA.23
Produtos recomendados
forma
powder or chunks
proporção de alimentação
lactide:glycolide 50:50
peso molecular
PEG average Mn 5,000 (by NMR)
PLGA average Mn 20,000 (by NMR)
cor
white to tan
temperatura de armazenamento
−20°C
Aplicação
Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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