799041

Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

PEG average M_n 5,000, PLGA average M_n 25,000, lactide:glycolide 50:50

• Sinônimo(s): PEG-PLGA, PEG-b-PLGA
• Fórmula linear: CH₃[C₂H₄O]_nO[(C₂H₂O₂)_x(C₃H₄O₂)_y]_mH
• Código UNSPSC: 12162002
• NACRES: NA.23

Propriedades

• Formulário: powder
• Nível de qualidade: 100
• peso molecular: PEG average M_n 5,000; PLGA average M_n 25,000
• composição: lactide:glycolide 50:50
• temperatura de armazenamento: 2-8°C

Descrição

Aplicação

Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs

Características e benefícios

• Good biocompatibility, low immunogenicity and good degradability.
• Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable