776246

SPhos Pd G3

97%

• Sinônimo(s): (2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl) [2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate
• Fórmula empírica (Notação de Hill): C₃₉H₄₈NO₅PPdS
• Número CAS: 1445085-82-4
• Peso molecular: 780.26
• Código UNSPSC: 12161600
• ID de substância PubChem: 329767824
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 97%
• forma: solid
• Características: generation 3
• adequação da reação: core: palladium; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; reaction type: Cross Couplings
• pf: 197-214 °C
• grupo funcional: phosphine
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CS(=O)(=O)O[Pd]c1ccccc1-c2ccccc2N.COc3cccc(OC)c3-c4ccccc4P(C5CCCCC5)C6CCCCC6
• InChI: 1S/C26H35O2P.C12H10N.CH4O3S.Pd/c1-27-23-17-11-18-24(28-2)26(23)22-16-9-10-19-25(22)29(20-12-5-3-6-13-20)21-14-7-4-8-15-21;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h9-11,16-21H,3-8,12-15H2,1-2H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;;;+1/p-1
• chave InChI: SCWODMZBSVVMRH-UHFFFAOYSA-M

Descrição

Descrição geral

SPhos Pd G3 is a third-generation (G3) Buchwald precatalyst that can be used in cross-coupling reactions for the formation of C-C, C-N, C-O, C-F, C-CF₃, and C-S bonds. It is air-, moisture-, and thermally stable and is highly soluble in a wide range of common organic solvents. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species, and accurate control of ligand: palladium ratio.

Aplicação

Pd catalyst for cross-coupling

SPhos Pd G3 can be used as a precatalyst in the Suzuki–Miyaura catalyst–transfer polymerization (SCTP) reaction of a wide spectrum of monomers, including electron-rich to electron-deficient (hetero)arenes. It is also used as a catalyst in the formation of a Csp³–Csp² bond between sterically hindered boronic hemiester and quinone diazide, which is the key intermediate step in the enantioselective synthesis of azamerone.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315 - H319 - H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable