468495

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate

97%

• Sinônimo(s): DiI
• Fórmula empírica (Notação de Hill): C₅₉H₉₇ClN₂O₄
• Número CAS: 41085-99-8
• Peso molecular: 933.87
• Beilstein: 8251870
• Número MDL: MFCD00142354
• Código UNSPSC: 12171500
• ID de substância PubChem: 24870519
• NACRES: NA.47

Propriedades

• Ensaio: 97%
• Formulário: crystalline
• composição: Carbon: 73.2-78.5%; ; Nitrogen: 2.7-3.3%
• técnica(s): titration: suitable
• cor: dark purple
• pf: 68 °C (dec.) (lit.)
• λmax: 549 nm
• ε (coeficiente de extinção): ≥10000 at 276-282 nm in methanol at 0.01 g/L; ≥130000 at 546-552 nm in methanol at 0.01 g/L; ≥70000 at 514-520 nm in methanol at 0.01 g/L
• aplicação(ões): diagnostic assay manufacturing; hematology; histology
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [O-]Cl(=O)(=O)=O.CCCCCCCCCCCCCCCCCCN1c2ccccc2C(C)(C)/C1=C\C=C\C3=[N+](CCCCCCCCCCCCCCCCCC)c4ccccc4C3(C)C
• InChI: 1S/C59H97N2.ClHO4/c1-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-41-50-60-54-46-39-37-44-52(54)58(3,4)56(60)48-43-49-57-59(5,6)53-45-38-40-47-55(53)61(57)51-42-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-2;2-1(3,4)5/h37-40,43-49H,7-36,41-42,50-51H2,1-6H3;(H,2,3,4,5)/q+1;/p-1
• chave InChI: JVXZRNYCRFIEGV-UHFFFAOYSA-M

Descrição

Descrição geral

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate is also called as Dil. It can be used to study HCV (Hepatitis C virus) cell interactions in the HCV entry process. It is used to label oxidized LDL (low-density lipoprotein) to quantify the uptake of DiI-oxLDL in human endothelial cells.

Aplicação

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate has been used in cytoskeletal staining, nuclear staining, retrograde labeling, counting of motor neurons and labelling of the retinal ganglion cell axons.

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate has been used in fluorescent labelling of mesenchymal stem cells (MSCs) and cerebral cortex. It has also been used in electromyogram (EMG) to determine awake and anesthetized states in mice.

Ações bioquímicas/fisiológicas

Lipophilic carbocyanine dye used primarily for optical recordings of membrane voltage and for studies of membrane fluidity. Retrograde stain for neurons; provides intense, long-lasting staining of live neurons in vivo and in vitro.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)