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442631

Sigma-Aldrich

Coumarin 6

98%

Sinônimo(s):

3-(2-Benzothiazolyl)-7-(diethylamino)coumarin, 3-(2-Benzothiazolyl)-N,N-diethylumbelliferylamine

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About This Item

Fórmula empírica (Notação de Hill):
C20H18N2O2S
Número CAS:
38215-36-0
Peso molecular:
350.43
Beilstein:
1085798
Número CE:
253-830-2
Número MDL:
MFCD00041869
Código UNSPSC:
12352103
ID de substância PubChem:
24867935
NACRES:
NA.23

Ensaio

98%

Formulário

solid

pf

208-210 °C (lit.)

λmax

444 nm

fluorescência

λem 505 nm in ethanol (Lasing peak 534 nm, lasing range 515 - 558 nm (DMSO), pump source XeCl (308 nm))

Desempenho do dispositivo OLED

ITO/Alq3:Coumarin 6/Mg:Ag

  • Color: green
  • Max. EQE: 2.5 %

cadeia de caracteres SMILES

CCN(CC)c1ccc2C=C(C(=O)Oc2c1)c3nc4ccccc4s3

InChI

1S/C20H18N2O2S/c1-3-22(4-2)14-10-9-13-11-15(20(23)24-17(13)12-14)19-21-16-7-5-6-8-18(16)25-19/h5-12H,3-4H2,1-2H3

chave InChI

VBVAVBCYMYWNOU-UHFFFAOYSA-N

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Descrição geral

Coumarin 6 (C6) is a derivative of coumarin with a benzothiazolyl group at the position 3. It emits fluorescence in solid and solution state and is used as fluorescent dye to stain organelles. C6 is majorly used as blue-green spectrum laser dye and is microenvironment sensitive.
Coumarin 6 is a fluorescent dye that belongs to the 7-diethylaminocoumarin series that can be used in a variety of biological activities. It can be used as a dopant that exhibits green light (500 nm) in optoelectronic applications.

Aplicação

Coumarin 6 dye can be used in the labeling and visualization of polymeric nanoparticles in biological applications, such as oral drug delivery systems for cancer. It can also be used in development of electroluminescent devices such as organic light emitting diodes (OLEDs).
Coumarin 6 has been used as a hydrophobic fluorescent dye
  • in block copolymer (BCP)-based micelle based drug delivery studies in glioma cell lines
  • in combination with flufenamic acid (FA) based nanoprodrug uptake in glioma cells
  • in poly(lactic-co-glycolic acid) (PLGA) based elvitegravir nanoprodrug uptake studies

Laser dye

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
SHBM8223
MKCL7084
MKCG8807
MKBV4602V
MKBR2011V

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7-Amino-4-(trifluoromethyl)coumarin ≥99%

Sigma-Aldrich

248924

7-Amino-4-(trifluoromethyl)coumarin

4-(Dicyanomethylene)-2-methyl-6-(4-dimethylaminostyryl)-4H-pyran Dye content 98 %

Sigma-Aldrich

410497

4-(Dicyanomethylene)-2-methyl-6-(4-dimethylaminostyryl)-4H-pyran

Novel elvitegravir nanoformulation approach to suppress the viral load in HIV-infected macrophages
Gong Y, et al.
Biochemistry and Biophysics Reports, 12, 214-219 (2017)
Fluorescent microcrystals obtained from coumarin 6 using the reprecipitation method
Fery-Forgues S, et al.
Journal of Fluorescence, 18(3-4), 619-624 (2008)
Photophysical and photochemical properties of Coumarin-6 molecules incorporated within MCM-48
Li D, et al.
Materials Letters, 59(17), 2120-2123 (2005)
Surface modification of indium tin oxide by plasma treatment: An effective method to improve the efficiency, brightness, and reliability of organic light emitting devices.
Wu CC, et al.
Applied Physics Letters, 70(11), 1348-1350 (1997)
Martina M Tzanova et al.
International journal of pharmaceutics, 592, 120100-120100 (2020-11-24)
The objective of this work was to develop and characterize solid lipid nanoparticle (SLN)-loaded mucoadhesive films to reveal their potential as successful drug formulations. SLNs based on lipid (Lipoid S100) and surfactant (polysorbate 80) were prepared using the solvent-injection method
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