About This Item
Produtos recomendados
Nível de qualidade
Ensaio
97%
forma
solid
pf
118-120 °C (lit.)
grupo funcional
ketone
cadeia de caracteres SMILES
COc1cc2CCC(=O)c2cc1OC
InChI
1S/C11H12O3/c1-13-10-5-7-3-4-9(12)8(7)6-11(10)14-2/h5-6H,3-4H2,1-2H3
chave InChI
IHMQOBPGHZFGLC-UHFFFAOYSA-N
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Descrição geral
Thiosemicarbazone derived from 5,6-dimethoxy-1-indanone inhibits bovine viral diarrhea virus infection.
Aplicação
5,6-Dimethoxy-1-indanone was used in the synthesis of 2,3-dimethoxy-11H-indeno[1,2-b]quinoline-6,10-dicarboxylic acid.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Bioorganic & medicinal chemistry, 7(12), 2801-2809 (2000-02-05)
A series of ring-substituted analogues of the topoisomerase inhibitor 11-oxo-11H-indeno[1,2-b]quinoline-6-carboxamides was prepared and evaluated. The compounds were prepared by Pfitzinger reaction of the appropriate isatin-7-carboxylic acids and 1-indanones, followed by selective thermal decarboxylation of the resulting tetracyclic diacids, subsequent oxidation
Journal of virology, 85(11), 5436-5445 (2011-03-25)
In the present work, we described the activity of the thiosemicarbazone derived from 5,6-dimethoxy-1-indanone (TSC), which we previously characterized as a new compound that inhibits bovine viral diarrhea virus (BVDV) infection. We showed that TSC acts at a point of
Bioorganic & medicinal chemistry, 25(15), 4055-4063 (2017-06-11)
A series of N
Bioorganic & medicinal chemistry, 17(19), 6914-6925 (2009-09-15)
Thienylhalomethylketones, whose chemical, biological, and pharmaceutical data are here reported, are the first irreversible inhibitors of GSK-3beta described to date. Their inhibitory activity is likely related to the cysteine residue present in the ATP-binding site, which is proposed as a
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