TEK
TEK tyrosine kinase, endothelial
Sinônimos:
CD202B, TIE-2, TIE2, VMCM, VMCM1
Espécies:
Human TEK (7010), Mouse Tek (21687), Rat Tek (89804), Zebrafish tek (30747), dog TEK (403714), domestic cat TEK (101091977), chicken TEK (427368), cow TEK (280939), domestic guinea pig Tek (100713324), naked mole-rat Tek (101710501)
ID UniProtKB:
ID do gene:
- Human(7010) Summary: The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq, Jul 2008]
- Mouse(21687) endothelial-specific receptor tyrosine kinase
- Rat(89804) TEK tyrosine kinase, endothelial
- Zebrafish(30747) TEK tyrosine kinase, endothelial
- dog(403714) TEK tyrosine kinase, endothelial
- domestic cat(101091977) TEK tyrosine kinase, endothelial
- chicken(427368) TEK tyrosine kinase, endothelial
- cow(280939) TEK tyrosine kinase, endothelial
- domestic guinea pig(100713324) TEK tyrosine kinase, endothelial
- naked mole-rat(101710501) TEK tyrosine kinase, endothelial
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ELISA
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Tie2/TEK Antibody, clone Ab33, clone Ab33, Upstate®, from mouse,
Reatividade de espécies
human, mouse, pig, rat
Aplicação
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-TIE2, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse
Aplicação
ELISA
immunohistochemistry
immunohistochemistry
Anti-phospho TIE2/TEK Antibody (Tyr992), 0.25 mg/mL, from rabbit,
Reatividade de espécies
bovine, human, mouse, rat, zebrafish
Aplicação
immunoprecipitation (IP)
inhibition assay
western blot
inhibition assay
western blot
Anti-phospho-TIE2 (pTyr1108) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Tie-2 Antibody, clone 1C5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
bovine, canine, human, monkey, mouse, rat
Aplicação
affinity binding assay
immunocytochemistry
western blot
immunocytochemistry
western blot
Small Molecule - Inhibitor
Número do produto
Descrição
Espécies
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Espécies
human
Proteins
Número do produto
Descrição
Espécies
Tie2 Protein, active, 10 µg, Active, N-terminal His6-tagged recombinant human Tie2 residues 771-end, for use in Kinase Assays.,
Espécies
human
TIE2 (771-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human