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Merck

SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

Sinônimos:
OAT4L, RST, URAT1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(116085) Summary: The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
  • Mouse(20521) solute carrier family 22 (organic anion/cation transporter), member 12
  • Rat(365398) solute carrier family 22 (organic anion/urate transporter), member 12
  • Horse(100055832) solute carrier family 22 (organic anion/urate transporter), member 12
  • dog(483761) solute carrier family 22 (organic anion/urate transporter), member 12
  • domestic cat(101100592) solute carrier family 22 (organic anion/urate transporter), member 12
  • domestic guinea pig(100721051) solute carrier family 22 (organic anion/urate transporter), member 12
  • naked mole-rat(101714998) solute carrier family 22 (organic anion/urate transporter), member 12
  • cow(526067) solute carrier family 22 (organic anion/urate transporter), member 12
  • sheep(101117630) solute carrier family 22 (organic anion/urate transporter), member 12

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-SLC22A12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Monoclonal Anti-SLC22A12 antibody produced in mouse, clone 2B5, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Anti-SLC22A12 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Lesinurad, ≥98% (HPLC),
Espécies
human
(±)-Sulfinpyrazone, analytical standard,
Espécies
human
Benzbromarone, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Benzbromarone, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Espécies
human
Sulfinpyrazone, European Pharmacopoeia (EP) Reference Standard,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human SLC22A12,
Espécies
human