SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
Sinônimos:
BESC2, ENaCa, ENaCalpha, SCNEA, SCNN1
Espécies:
Human SCNN1A (6337), Mouse Scnn1a (20276), Rat Scnn1a (25122), cow SCNN1A (282348), sheep SCNN1A (443488), naked mole-rat Scnn1a (101700410), domestic guinea pig Scnn1a (100135613), chicken SCNN1A (396050), domestic cat SCNN1A (101091122), dog SCNN1A (403650)
ID UniProtKB:
ID do gene:
- Human(6337) Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
- Mouse(20276) sodium channel, nonvoltage-gated 1 alpha
- Rat(25122) sodium channel, nonvoltage-gated 1 alpha
- cow(282348) sodium channel, non-voltage-gated 1 alpha subunit
- sheep(443488) sodium channel, non-voltage-gated 1 alpha subunit
- naked mole-rat(101700410) sodium channel, non-voltage-gated 1 alpha subunit
- domestic guinea pig(100135613) sodium channel, nonvoltage-gated 1 alpha
- chicken(396050) sodium channel, non-voltage-gated 1 alpha subunit
- domestic cat(101091122) sodium channel, non-voltage-gated 1 alpha subunit
- dog(403650) sodium channel, non-voltage-gated 1 alpha subunit
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Small Molecule - Antagonist
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Antibodies
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Aplicação
Monoclonal Anti-ENaC alpha antibody produced in mouse, clone 14E10,
Reatividade de espécies
mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Anti-SCNN1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Monoclonal Anti-ENaC alpha-FITC antibody produced in mouse, clone 14E10,
Reatividade de espécies
mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Monoclonal Anti-ENaC alpha antibody produced in mouse, clone 2G4,
Reatividade de espécies
mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Anti-SCNN1A antibody produced in rabbit, 1 mg/mL, affinity isolated antibody,
Reatividade de espécies
mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
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Small Molecule - Inhibitor
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