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Merck

PTGER4

prostaglandin E receptor 4 (subtype EP4)

Sinônimos:
EP4, EP4R
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5734) Summary: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
  • Mouse(19219) prostaglandin E receptor 4 (subtype EP4)
  • Rat(84023) prostaglandin E receptor 4 (subtype EP4)
  • domestic guinea pig(100192398) prostaglandin E receptor 4 (subtype EP4)
  • Domestic Rabbit(100009081) prostaglandin E receptor 4 (subtype EP4)
  • naked mole-rat(101723705) prostaglandin E receptor 4 (subtype EP4)
  • cow(282331) prostaglandin E receptor 4 (subtype EP4)
  • sheep(101104343) prostaglandin E receptor 4 (subtype EP4)
  • sheep(443222) prostaglandin E receptor 4 (subtype EP4)
  • chicken(427183) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(101094734) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(100169968) prostaglandin E receptor 4 (subtype EP4)
  • dog(403589) prostaglandin E receptor 4 (subtype EP4)

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
Prostaglandin E1, ≥98% (HPLC), synthetic,
Espécies
human, mouse
Prostaglandin E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
Espécies
human, mouse
Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture,
Espécies
human, mouse
Prostaglandin E2, synthetic, powder, BioReagent, suitable for cell culture,
Espécies
human, mouse
Prostaglandin E2, γ-irradiated, powder, BioXtra, suitable for cell culture,
Espécies
human, mouse

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Prostaglandin E1, ≥98% (HPLC), synthetic,
Espécies
human, mouse
Prostaglandin E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
Espécies
human, mouse
Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture,
Espécies
human, mouse
Prostaglandin E2, synthetic, powder, BioReagent, suitable for cell culture,
Espécies
human, mouse
Prostaglandin E2, ≥93% (HPLC), synthetic,
Espécies
mouse, human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PTGER4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Anti-EP4 Prostaglandin Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
canine, human
Aplicação
ELISA
western blot
Anti-PE2R4 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

western blot

Small Molecule - Mixed Agonist/Antagonist

Número do produto
Descrição
Espécies
Prostaglandin E2, ≥93% (HPLC), synthetic,
Espécies
mouse, human
Indometacina, 98.5-100.5% (in accordance with EP),
Espécies
human, mouse, rat

Proteins

Número do produto
Descrição
Espécies
ChemiScreen Membrane Preparation
Recombinant Human EP4 Prostanoid Receptor
, Human EP4 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PTGER4,
Espécies
human
MISSION® esiRNA, targeting mouse Ptger4,
Espécies
mouse