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Merck

PRKCD

protein kinase C, delta

Sinônimos:
MAY1, PKCD, nPKC-delta
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5580) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(18753) protein kinase C, delta
  • Rat(170538) protein kinase C, delta
  • chicken(415905) protein kinase C, delta
  • dog(494005) protein kinase C, delta
  • domestic cat(101087716) protein kinase C, delta
  • cow(505708) protein kinase C, delta
  • sheep(100294651) protein kinase C, delta
  • sheep(101107639) protein kinase C, delta
  • naked mole-rat(101718422) protein kinase C, delta
  • Domestic Rabbit(100008966) protein kinase C, delta
  • domestic guinea pig(100726624) protein kinase C, delta

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
Oleic acid, ≥99% (GC),
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PRKCD antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-PRKCD antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-PKCδ (Ser664) Antibody, Upstate®, from rabbit,
Reatividade de espécies
human
Aplicação
western blot
Anti-Protein Kinase Cδ antibody produced in rabbit, whole antiserum,
Reatividade de espécies
rat
Aplicação
dot blot
microarray

western blot
Anti-PKC δ antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Phorbol 12,13-dibutyrate, ≥98% (TLC), powder,
Espécies
mouse
H-7 dihydrochloride, ≥98% (HPLC),
Espécies
human
Tamoxifen citrate salt, ≥99%,
Espécies
human
Oleic acid, ≥99% (GC),
Espécies
human
UCN-01, ≥97% (HPLC), powder,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
PKCδ Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 2-end, of human PKCδ. For use in Kinase Assays.,
Espécies
human
PKC-δ, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human
Protein Kinase Cδ isozyme human, >95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PRKCD,
Espécies
human
MISSION® esiRNA, targeting mouse Prkcd,
Espécies
mouse