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Merck

KCNA4

potassium voltage-gated channel, shaker-related subfamily, member 4

Sinônimos:
HBK4, HK1, HPCN2, HUKII, KCNA4L, KCNA8, KV1.4, PCN2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(3739) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.[provided by RefSeq, Mar 2011]
  • Mouse(16492) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Rat(25469) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Zebrafish(559036) potassium voltage-gated channel, shaker-related subfamily, member 4
  • chicken(395721) potassium voltage-gated channel, shaker-related subfamily, member 4
  • cow(281880) potassium voltage-gated channel, shaker-related subfamily, member 4
  • domestic cat(101084479) potassium voltage-gated channel, shaker-related subfamily, member 4
  • dog(485427) potassium voltage-gated channel, shaker-related subfamily, member 4
  • domestic guinea pig(100725985) potassium voltage-gated channel, shaker-related subfamily, member 4
  • naked mole-rat(101706863) potassium voltage-gated channel, shaker-related subfamily, member 4
  • sheep(101118217) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Domestic Rabbit(100328568) potassium voltage-gated channel, shaker-related subfamily, member 4

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-KCNA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Monoclonal Anti-KCNA4 antibody produced in mouse, clone S13-31, 1 mg/mL, purified immunoglobulin,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Potassium Channel Kv1.4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reatividade de espécies
mouse, rat
Aplicação
immunohistochemistry
western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Guanidina, for molecular biology, ≥99%,
Espécies
human
Guanidina, ≥98%,
Espécies
human
Guanidina, organic base and chaeotropic agent, ≥99% (titration),
Espécies
human
Guanidina, ,
Espécies
human
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human KCNA4,
Espécies
human
MISSION® esiRNA, targeting mouse Kcna4,
Espécies
mouse