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Merck

CRH

corticotropin releasing hormone

Sinônimos:
CRF
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1392) Summary: Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010]
  • Mouse(12918) corticotropin releasing hormone
  • Rat(81648) corticotropin releasing hormone
  • chicken(404297) corticotropin releasing hormone
  • dog(486977) corticotropin releasing hormone
  • domestic cat(692345) corticotropin releasing hormone
  • cow(280755) corticotropin releasing hormone
  • sheep(101121525) corticotropin releasing hormone
  • Domestic Rabbit(100301553) corticotropin releasing hormone
  • domestic guinea pig(100719294) corticotropin releasing hormone
  • naked mole-rat(101717831) corticotropin releasing hormone

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
Astressin, ≥90% (HPLC),
Espécies
mouse, human, rat

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Corticotropin Releasing Factor Antagonist, ≥97% (HPLC),
Espécies
mouse, human, rat

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Monoclonal Anti-CRH antibody produced in mouse, clone 2B11, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Anti-CRH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Anti-CRH antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
Anti-Corticotropin Releasing Factor antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
bovine, canine, frog, human, mouse, pig, rat, sheep
Aplicação
immunohistochemistry
microarray

radioimmunoassay

Proteins

Número do produto
Descrição
Espécies
Corticotropin Releasing Factor human, rat, ≥95% (HPLC), powder,
Espécies
human
Corticotropin Releasing Factor, Human and Rat, An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla.,
Espécies
human
Corticotropin Releasing Factor bovine, ≥90% (HPLC), Synthetic,
Espécies
cow
Corticotropin Releasing Factor Fragment 6-33 human, rat, ≥97% (HPLC),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Crh,
Espécies
mouse
MISSION® esiRNA, targeting human CRH,
Espécies
human