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535140

Millipore

Protease Inhibitor Cocktail III

Animal-Free, liquid, for the inhibition of aspartic, cysteine, serine proteases and aminopeptidases

Synonyme(s) :

Animal free Protease inhibitor

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About This Item

Code UNSPSC :
12352200
Nomenclature NACRES :
NA.54

product name

Protease Inhibitor Cocktail Set III, Animal-Free, Protease Inhibitor Cocktail Set III, Animal-Free, is a cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine & serine proteases & aminopeptidases.

Forme

liquid

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
avoid repeated freeze/thaw cycles

Conditions d'expédition

wet ice

Température de stockage

−20°C

Description générale

A cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine, and serine proteases as well as aminopeptidases. This cocktail is recommended for use with mammalian cell and tissue extracts. Each vial contains 100 mM AEBSF, HCl (Cat. No. 101500), 80 µM Aprotinin (Cat. No. 616371), 5 mM Bestatin (Cat. No. 200484), 1.5 mM E-64 (Cat. No. 324890), 2 mM Leupeptin Hemisulfate (Cat. No. 108975) and 1 mM Pepstatin A (Cat. No. 516482). Available as 1 ml vial or a set of 5 x 1 ml.
A cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine, and serine proteases as well as aminopeptidases. This cocktail is recommended for use with mammalian cell and tissue extracts. One ml is sufficient for approximately 20 g tissue. Note: 1 set = 5 x 1 ml vials.

Actions biochimiques/physiologiques

Cell permeable: no
Primary Target
Aspartic, cysteine, and serine proteases as well as aminopeptidases
Product does not compete with ATP.
Reversible: no

Avertissement

Toxicity: Irritant (B)

Forme physique

In 1 ml DMSO.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

188.6 °F

Point d'éclair (°C)

87 °C

Certificats d'analyse (COA)

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Kimberly D Herman et al.
Frontiers in immunology, 13, 956991-956991 (2022-08-16)
Dysregulated neutrophilic inflammation can be highly destructive in chronic inflammatory diseases due to prolonged neutrophil lifespan and continual release of histotoxic mediators in inflamed tissues. Therapeutic induction of neutrophil apoptosis, an immunologically silent form of cell death, may be beneficial
Changhwan Yeo et al.
International journal of molecular sciences, 23(8) (2022-04-24)
Osteoarthritis (OA) causes persistent pain, joint dysfunction, and physical disability. It is the most prevalent type of degenerative arthritis, affecting millions of people worldwide. OA is currently treated with a focus on pain relief, inflammation control, and artificial joint surgery.
Jessica A O Zimmerman et al.
RSC medicinal chemistry, 12(2), 203-212 (2021-05-29)
Glucocorticoids (GCs) are widely used, potent anti-inflammatory and chemotherapeutic drugs. They work by binding to the glucocorticoid receptor (GR), a ligand-activated transcription factor, inducing translocation to the nucleus and regulation of genes that influence a variety of cellular activities. Despite
Danielle T Phillippi et al.
Particle and fibre toxicology, 19(1), 10-10 (2022-02-10)
The gut microbiota plays a vital role in host homeostasis and is associated with inflammation and cardiovascular disease (CVD) risk. Exposure to particulate matter (PM) is a known mediator of inflammation and CVD and is reported to promote dysbiosis and
David M Box et al.
Children (Basel, Switzerland), 9(3) (2022-03-26)
In utero inflammation is associated with bronchopulmonary dysplasia (BPD) in preterm infants. We hypothesized that maternal tobacco exposure (TE) might induce placental neutrophil infiltration, increasing the risk for BPD. We compared the composite outcome of BPD and death in a
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