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Aspergillus niger citric acid accumulation: do we understand this well working black box?

Applied microbiology and biotechnology (2003-04-17)
Levente Karaffa, Christian P Kubicek
ZUSAMMENFASSUNG

This Mini-Review summarizes the current knowledge on the biochemical and physiological events leading to massive citric acid accumulation by Aspergillus niger under industrially comparable conditions, thereby particularly emphasizing the roles of glycolytic flux and its control, excretion of citric acid from the mitochondria and the cytosol, and the critical fermentation variables. The potential of novel techniques for metabolic analysis and genomic approaches in understanding this fermentation is also discussed.

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Sigma-Aldrich
Zitronensäure, meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance)
Sigma-Aldrich
Zitronensäure, ≥99.5%, FCC, FG
Sigma-Aldrich
Zitronensäure, ACS reagent, ≥99.5%
Sigma-Aldrich
Zitronensäure, anhydrous, suitable for cell culture, suitable for plant cell culture
USP
Zitronensäure, United States Pharmacopeia (USP) Reference Standard
Sigma-Aldrich
Zitronensäure, BioUltra, anhydrous, ≥99.5% (T)
Sigma-Aldrich
Zitronensäure, 99%
Supelco
Citronensäure, wasserfrei, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Zitronensäure, anhydrous, free-flowing, Redi-Dri, ACS reagent, ≥99.5%
Supelco
Zitronensäure, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Zitronensäure, anhydrous, European Pharmacopoeia (EP) Reference Standard