Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines.

Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines.

Organic & biomolecular chemistry (2012-11-13)

Lan-Tao Li, Hong-Ying Li, Li-Juan Xing, Li-Juan Wen, Peng Wang, Bin Wang

ZUSAMMENFASSUNG

A one-pot dual functionalization of indoles has been developed. The simultaneous C3-formylation and N-aminomethylation of indoles can be achieved using readily available potassium iodide as a catalyst and tert-butyl peroxybenzoate as a co-oxidant.

MATERIALIEN

Produktnummer

Marke

Produktbeschreibung

221945

Sigma-Aldrich

Kaliumiodid, ACS reagent, ≥99.0%

207969

Sigma-Aldrich

Kaliumiodid, ReagentPlus^®, 99%

651818

Sigma-Aldrich

Goldätzmittel, Standard

204102

Sigma-Aldrich

Kaliumiodid, ≥99.99% trace metals basis

60399

Sigma-Aldrich

Kaliumiodid, BioUltra, ≥99.5% (AT)

236233

Sigma-Aldrich

N-Methylanilin, ≥99%

M29304

Sigma-Aldrich

N-Methylanilin, 98%

P8166

Sigma-Aldrich

Kaliumiodid, suitable for plant cell culture

03124-M

Sigma-Aldrich

Kaliumiodid, puriss., meets analytical specification of Ph. Eur. BP, USP, 99.0-100.5% (calc. to the dried substance)

429422

Sigma-Aldrich

Kaliumiodid, AnhydroBeads^™, −10 mesh, 99.998% trace metals basis

60422

Sigma-Aldrich

Kaliumiodid, tested according to Ph. Eur.

P2963

Sigma-Aldrich

Kaliumiodid, BioXtra, ≥99.0%

209872

Sigma-Aldrich

4-tert-Butyl-N,N-dimethylanilin, 98%

49636

Supelco

N-Methylanilin, analytical standard

65760

Sigma-Aldrich

N-Methylanilin, purum, ≥98.0% (GC)