1224937

Dofetilid

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): N-[4-[2-[Methyl-[2-[4-[(methylsulfonyl)-amino]-phenoxy]-ethyl]-amino]-ethyl]-phenyl]-methansulfonamid
• Empirische Formel (Hill-System): C₁₉H₂₇N₃O₅S₂
• CAS-Nummer: 115256-11-6
• Molekulargewicht: 441.56
• MDL-Nummer: MFCD00869707
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329749665
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: dofetilide
• Hersteller/Markenname: USP
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc2ccc(NS(C)(=O)=O)cc2
• InChI: 1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3
• InChIKey: IXTMWRCNAAVVAI-UHFFFAOYSA-N
• Angaben zum Gen: human ... KCNH2(3757)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Dofetilide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem./physiol. Wirkung

Dofetilide is a Class III antiarrhythmic and hERG channel blocker. Dofetilide selectively blocks the rapid component of the delayed rectifier outward potassium current (IKr).

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H360Df,H362,H410
• P-Sätze: P202 - P260 - P263 - P264 - P273 - P308 + P313
• Gefahreneinstufungen: Aquatic Chronic 1 - Lact. - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable