PHL89766

Protocatechusäure

phyproof^® Reference Substance

• Synonym(e): 3,4-Dihydroxy-benzoesäure, Protocatechusäure
• Lineare Formel: (HO)₂C₆H₃CO₂H
• CAS-Nummer: 99-50-3
• Molekulargewicht: 154.12
• Beilstein: 1448841
• MDL-Nummer: MFCD00002509
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: primary reference standard
• Produktlinie: phyproof^® Reference Substance
• Assay: ≥98.0% (HPLC)
• Form: solid
• Hersteller/Markenname: PhytoLab
• mp (Schmelzpunkt): 197-200 °C (dec.) (lit.)
• SMILES String: OC(=O)c1ccc(O)c(O)c1
• InChI: 1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)
• InChIKey: YQUVCSBJEUQKSH-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Anwendung

• Bronchom assuages airway hyperresponsiveness in house dust mite-induced mouse model of allergic asthma and moderates goblet cell metaplasia, sub-epithelial fibrosis along with changes in Th2 cytokines and chemokines.: This study highlights the anti-inflammatory properties of Protocatechuic acid, demonstrating its potential as a natural phenolic compound in pharmacological studies and its role in modulating immune responses (Balkrishna et al., 2024).


• Exploring the Efficacy of Hydroxybenzoic Acid Derivatives in Mitigating Jellyfish Toxin-Induced Skin Damage: Insights into Protective and Reparative Mechanisms.: This research provides insights into the protective and reparative mechanisms of Protocatechuic acid against toxin-induced skin damage, emphasizing its antioxidant properties and applications in biochemistry and dermatology (Geng et al., 2024).


• Patterns of alteration in boar semen quality from 9 to 37 months old and improvement by protocatechuic acid.: This article investigates the role of Protocatechuic acid in improving semen quality, showcasing its benefits in reproductive biology and potential applications as an antioxidant agent in animal science (Hu et al., 2024).


• Phytochemical Analysis and Antioxidant Effects of Prunella vulgaris in Experimental Acute Inflammation.: The study details the antioxidant effects of Protocatechuic acid in mitigating acute inflammation, underlining its importance in pharmacological studies and biochemical assays for anti-inflammatory research (Mirza et al., 2024).


• Phenolic compound profiling and antioxidant potential of different types of Schisandra henryi in vitro cultures.: This research highlights the antioxidant potential and phenolic profiling of Protocatechuic acid, making it a valuable reagent for biochemical assays and studies on natural phenolic compounds (Jafernik et al., 2024).

Biochem./physiol. Wirkung

Chemopräventiv bei der Krebsentstehung in verschiedenen Tiermodellen. Hemmt die Zellproliferation in der Post-Initiationsphase.

Sonstige Hinweise

This compound is commonly found in plants of the genus: allium carum cinnamomum curcuma ginkgo humulus melissa pimpinella thymus

Rechtliche Hinweise

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable