581322-U

Ascentis^® C18 (3 µm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

• Synonym(e): Ascentis RP18 HPLC Column
• UNSPSC-Code: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Eigenschaften

• product name: Ascentis^® C18 HPLC-Säule, 3 μm particle size, L × I.D. 15 cm × 4.6 mm
• Materialien: stainless steel column
• Qualitätsniveau: 100
• Agentur: suitable for USP L1 (Similar to Phenomenex Luna C18)
• Produktlinie: Ascentis^®
• Leistungsmerkmale: endcapped
• Hersteller/Markenname: Ascentis^®
• Verpackung: 1 ea of
• Kennzeichnungsgrad: 25% Carbon loading
• Parameter: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• Methode(n): HPLC: suitable; LC/MS: suitable
• L × ID: 15 cm × 4.6 mm
• Oberflächenbereich: 450 m²/g
• Oberflächendeckung: 3.7 μmol/m²
• Verunreinigungen: <5 ppm metals
• Matrix: fully porous particle; silica gel high purity, spherical
• Aktive Matrixgruppe: C18 (octadecyl) phase
• Partikelgröße: 3 μm
• Porengröße: 100 Å
• operating pH range: 2-8
• Anwendung(en): food and beverages
• Trenntechnik: reversed phase

Beschreibung

Allgemeine Beschreibung

Die Ascentis C18 ist eine äußerst stabile und zuverlässige HPLC-Säule, die eine symmetrische Peak-Form sowie eine ausgezeichnete Retention auch schwieriger Verbindungen ermöglicht.

Anwendung

• A dilute-and-shoot liquid chromatography-tandem mass spectrometry method for urinary 18-hydroxycortisol quantification and its application in establishing reference intervals: This paper details the application of Ascentis^® C18 columns in a clinical setting to measure cortisol levels in urine. The method provides a fast, accurate, and reliable way to assess patient hormonal profiles, critical for diagnosing endocrine disorders (Zhao et al., 2022).


• A Comparative Study on Analysis of Ginsenosides in American Ginseng Root Residue by HPLC-DAD-ESI-MS and UPLC-HRMS-MS/MS: Utilizing Ascentis^® C18, this study compares different analytical methods for quantifying ginsenosides. It showcases the column′s adaptability and precision in natural product research, essential for ensuring the quality and efficacy of herbal medicines (Hsu et al., 2022).


• Validation of a Rapid and Easy-to-Apply Method to Simultaneously Quantify Co-Loaded Dexamethasone and Melatonin PLGA Microspheres by HPLC-UV: Highlighting the Ascentis^® C18′s effectiveness in pharmaceutical formulations, this research demonstrates its capacity to analyze complex drug delivery systems, contributing to the development of more effective therapeutic solutions (Brugnera et al., 2022).


• Simultaneous determination of ivermectin, clorsulon and their related substances in an injectable finished product by a stability-indicating RP-HPLC method: This publication illustrates the application of the Ascentis^® C18 in veterinary medicine, providing crucial insights into drug stability and composition which are vital for regulatory compliance and animal safety (Padivitage et al., 2022).

Leistungsmerkmale und Vorteile

• Ausgezeichnete Retention
• Symmetrische Peak-Form
• Hohe Reproduzierbarkeit
• Vollständig LC-MS-kompatibel

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Rechtliche Hinweise

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable