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575664-U

Supelco

Supel-Select SCX SPE 96-well Plate

bed wt. 30 mg/well, pk of 1

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About This Item

UNSPSC-Code:
41104018
NACRES:
NB.21

Materialien

PE frit (20 μm)
polypropylene hardware

Qualität

MS Friendly

Zusammensetzung

bed wt., 30 mg/well

Verpackung

pk of 1

Methode(n)

solid phase extraction (SPE): suitable

Oberflächenbereich

160-420 m2/g

Matrix

Sulfonic acid functionalized hydrophilic modified styrene polymer particle platform

Aktive Matrixgruppe

sulfonic acid phase

Partikelgröße

50-70 μm

Porengröße

80-200 Å pore size

Anwendung(en)

food and beverages

Trenntechnik

ion exchange

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Allgemeine Beschreibung

Retention Mechanism: Ion-Exchange
Sample Matrix Compatibility: Aqueous solutions (biological fluids, water)

  • Sulfonic acid functionalized hydrophilic modified styrene polymer
  • Developed for the extraction of a highly broad range of compounds from aqueous samples
  • Retention predominately based on ion-exchange; however, because the phase is hydrophilic modified, it is amenable to polar compounds as well.

Leistungsmerkmale und Vorteile

  • Excellent sample prep performance at a lower price
  • Amenable to generic methodology - save time, money, and headache during method development
  • Greater capacity allows for smaller bed weights = smaller elution volumes = time savings in sample processing
  • Resistance to overdrying allows for more robust methdology
  • Low UV and MS extractables for lower background and greater sensitivity
  • Stringent production and QC guidelines offer greater lot-to-lot, tube-to-tube, and well-to-well consistency for improved accuracy and precision

Rechtliche Hinweise

Supel is a trademark of Sigma-Aldrich Co. LLC

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Artikel

Shown here is the chiral separation of amphetamine enantiomers under MS-compatible conditions on Astec CHIROBIOTIC® V2 after extraction from urine using Supel™-Select SCX SPE 96-well plates. The highest grade mobile phase solvents and additives were used to supply low background interference and low particulate contaminants for robust, trouble-free operation. Cerilliant CRMs provided reliable identification and quantification.

SPE retention mechanism in this case is based on the electrostatic attraction of charged functional groups of the analyte(s) to oppositely charged functional groups on the sorbent.

Protokolle

Optimized sample prep and chiral chromatography methods for the LC/MS analysis of these drug enantiomers in urine

In this study, optimized methods are presented for sample preparation and chiral chromatography for the LC/MS analysis of amphetamine and methamphetamine enantiomers in urine.

LC/MS Analysis of Methamphetamine Enantiomers on Astec® CHIROBIOTIC® V2 in Urine after SPE using Supel™-Select SCX

Retention occurs through polar interaction between the sorbent and analytes. Typical sample matrices that can be employed in normal-phase SPE include hydrocarbon or fatty oils diluted in a solvent like hexane, isooctane, chlorinated solvent, THF, diethyl ether, or ethyl acetate.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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