T1019

(±)-Thiopental

• Synonym(e): 5-Ethyl-5-(1-methylbutyl)-2-thiobarbitursäure, Thiopenton
• Empirische Formel (Hill-System): C₁₁H₁₈N₂O₂S
• CAS-Nummer: 76-75-5
• Molekulargewicht: 242.34
• EG-Nummer: 200-984-3
• MDL-Nummer: MFCD00057564
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 24899925
• NACRES: NA.77

Eigenschaften

• Arzneimittelkontrolle: USDEA Schedule III; regulated under CDSA - not available from Sigma-Aldrich Canada
• Qualitätsniveau: 200
• Löslichkeit: ethanol: complete 50 mg/mL
• Ersteller: Abbott
• SMILES String: CCCC(C)C1(CC)C(=O)NC(=S)NC1=O
• InChI: 1S/C11H18N2O2S/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)
• InChIKey: IUJDSEJGGMCXSG-UHFFFAOYSA-N
• Angaben zum Gen: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

Beschreibung

Anwendung

(±)-Thiopental was used to transiently anesthetize rats for in vivo NMR spectroscopy.

Biochem./physiol. Wirkung

Thiopental is an anesthetic that decreases cerebral metabolic rate without altering the blood flow or oxygen consumption.

Leistungsmerkmale und Vorteile

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves