Direkt zum Inhalt
Merck
Alle Fotos(1)

Key Documents

SRP4210

Sigma-Aldrich

GRO/KC from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

Synonym(e):

CXCL1, GRO α, GRO1, Growth-regulated α protein, NAP-3

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

MDL-Nummer:
MFCD00165726
UNSPSC-Code:
12352200
NACRES:
NA.32

Biologische Quelle

mouse

Rekombinant

expressed in E. coli

Assay

≥98% (HPLC)
≥98% (SDS-PAGE)

Form

lyophilized

Wirksamkeit

10-100 ng/mL

Mol-Gew.

~7.8 kDa

Verpackung

pkg of 20 μg

Verunreinigungen

endotoxin, tested

NCBI-Hinterlegungsnummer

P12850

UniProt-Hinterlegungsnummer

P12850

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

mouse ... Cxcl1(14825)

Allgemeine Beschreibung

Growth-regulated oncogenes (GRO)/keratinocyte chemoattractant (KC) belongs to the growing inflammatory protein superfamily. KC is characterized with four conserved cysteine residues with a CXC motif.
Mouse KC (also known as mouse GRO-α) belongs to the C-X-C family of chemokines. Mouse KC is a 7.8 kDa protein containing 72 amino acid residues.

Biochem./physiol. Wirkung

Growth-regulated oncogenes (GRO)/keratinocyte chemoattractant (KC) plays a vital role in wound healing and inflammation. In rat, serum levels of GRO/KC can be used as a predictive biomarker for inhibitory effect of chemopreventive agents on esophageal carcinogenesis.

Physikalische Form

Sterile filtered and then lyophilized without any additives.

Rekonstituierung

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1 mg/mL. This solution can be diluted into other aqueous buffers.

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Multiple berry types prevent N-nitrosomethylbenzylamine-induced esophageal cancer in rats
Stoner GD, et al.
Pharmaceutical Research, 27(6), 1138-1145 (2010)
Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue
Iida NAOKO and Grotendorst GR
Molecular Cell Biology, 10(10), 5596-5599 (1990)
Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue.
Iida N A O K O, et al.
Molecular and Cellular Biochemistry, 10(10), 5596-5599 (1990)
Aimalie L Hardaway et al.
Clinical & experimental metastasis, 32(4), 353-368 (2015-03-25)
Increased bone marrow adiposity is a common feature of advanced age, obesity and associated metabolic pathologies. Augmented numbers of marrow adipocytes positively correlate with dysregulated bone remodeling, also a well-established complication of metastatic disease. We have shown previously that marrow
Yuan Sun et al.
The journal of pain : official journal of the American Pain Society, 15(8), 856-866 (2014-06-03)
Chronic opioid consumption increases postoperative pain. Epigenetic changes related to chronic opioid use and surgical incision may be partially responsible for this enhancement. The CXCL1/CXCR2 signaling pathway, implicated in several pain models, is known to be epigenetically regulated via histone

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.