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Merck

RAB0374

Sigma-Aldrich

Mouse MPO ELISA Kit

for plasma and cell culture supernatant

Synonym(e):

MPO, Myeloperoxidase

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About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

Speziesreaktivität

mouse

Verpackung

kit of 96 wells (12 strips x 8 wells)

Methode(n)

ELISA: suitable
capture ELISA: suitable

Aufnahme

sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 600 pg/mL
standard curve range: 0.61-150 ng/mL

Nachweisverfahren

colorimetric

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

mouse ... Mpo(17523)

Allgemeine Beschreibung

The Mouse MPO (Myeloperoxidase) ELISA (Enzyme- Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse MPO in plasma and cell culture supernatants.

Immunogen

Recombinant Mouse Myeloperoxidase

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem./physiol. Wirkung

Myeloperoxidase (MPO) has a crucial role to play in the destruction of various microorganisms and foreign cells, such as bacteria, fungi, viruses, red cells, and malignant and nonmalignant nucleated cells. MPO catalyzes the production of number of reactive oxidant species (ROS) that influence tissue damage during inflammation. MPO and its downstream inflammatory pathways function as a potent therapeutic target for prophylaxis of atherosclerotic cardiovascular disease. MPO catalyzes the synthesis of polychlorinated dibenzo(p)dioxins and furans (PCDD/F) from precursors such as chlorophenols in the presence of hydrogen peroxide (H2O2).

Sonstige Hinweise

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDB

  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)SDB

  • RABSTOP3ELISA Stop Solution (Item I)SDB

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDB

  • RABWASH420X Wash Buffer (Item B)SDB

Piktogramme

Corrosion

Signalwort

Warning

H-Sätze

P-Sätze

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Clinical manifestation of myeloperoxidase deficiency.
Lanza F, et al.
Journal of Molecular Medicine, 76, 676-681 (1998)
Maiko de Kerckhove et al.
EMBO molecular medicine, 10(10) (2018-09-02)
Argonaute 2 bound mature microRNA (Ago2-miRNA) complexes are key regulators of the wound inflammatory response and function in the translational processing of target mRNAs. In this study, we identified four wound inflammation-related Ago2-miRNAs (miR-139-5p, miR-142-3p, miR-142-5p, and miR-223) and show
Troy Perry et al.
PloS one, 12(9), e0184660-e0184660 (2017-09-19)
Ileocolic resection (ICR) is the most common intestinal resection performed for Crohn's disease, with recurrences commonly occurring at the site of the anastomosis. This study used an animal model of ICR in wild-type mice to examine immunologic changes that developed
Thibaut Van Zele et al.
American journal of rhinology & allergy, 28(3), 192-198 (2014-07-02)
Surgery for chronic rhinosinusitis with nasal polyps (CRSwNPs) often fails because of recurrence of disease. So far, we do not know if specific cytokine profiles are linked to recurrence after functional endoscopic sinus surgery (FESS) or can predict recurrence. In
Aleksandra Topic et al.
Fetal and pediatric pathology, 36(4), 294-303 (2017-05-10)
The significance of oxidative stress in pathogenesis of childhood asthma was recognized, but its role in the clinical manifestations of disease is still unclear. The study was conducted in 96 asthmatic children. The urinary biomarker of oxidative stress, 8-oxo-7,8-dihydro-2-deoxyguanosine (8-oxodG/creatinine)

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