SML2262

Ramelteon

• Synonym(e): Ramelteon solution, (S)-N-[2-(1,6,7,8-Tetrahydro-2H-indeno-[5,4-b]furan-8-yl)ethyl]propionamide, N-[2-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide, TAK 375, TAK-375
• Empirische Formel (Hill-System): C₁₆H₂₁NO₂
• CAS-Nummer: 196597-26-9
• Molekulargewicht: 259.34
• MDL-Nummer: MFCD08067736
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Form: powder
• Optische Aktivität: [α]/D -50 to -60°, c = 1.0 in chloroform-d
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: CCC(NCC[C@H]1C(C(CCO2)=C2C=C3)=C3CC1)=O
• InChI: 1S/C16H21NO2/c1-2-15(18)17-9-7-12-4-3-11-5-6-14-13(16(11)12)8-10-19-14/h5-6,12H,2-4,7-10H2,1H3,(H,17,18)/t12-/m0/s1
• InChIKey: YLXDSYKOBKBWJQ-LBPRGKRZSA-N
• Angaben zum Gen: human ... MTNR1A(4543) , MTNR1B(4544)

Beschreibung

Biochem./physiol. Wirkung

Ramelteon is a cell penetrant, potent and selective agonist at MT1/MT2 melatonin receptor that exhibits sleep-promoting properties. It is not binding to GABA receptor complex. Ramelteon is an analog of melatonin recently approved to treat insomnia.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable