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Merck

SAB4700706

Sigma-Aldrich

Monoclonal Anti-CD90-FITC antibody produced in mouse

clone 5E10, purified immunoglobulin, buffered aqueous solution

Synonym(e):

Anti-Thy-1

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.44

Biologische Quelle

mouse

Qualitätsniveau

Konjugat

FITC conjugate

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

5E10, monoclonal

Form

buffered aqueous solution

Speziesreaktivität

pig, nonhuman primates, human, dog

Methode(n)

flow cytometry: suitable
immunoblotting: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... THY1(7070)

Allgemeine Beschreibung

Thy-1 cell surface antigen (Thy-1)/CD90 (cluster of differentiation 90) is a 25–37kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein. It was first detected in the T cells of mice. Thy-1 is expressed in thymocytes, T cells, neurons, hematopoietic stem cells, cancer stem cells, endothelial cells and fibroblasts. This gene is located on human chromosome 11q23.

Immunogen

HEL erythroleukemia cells

Biochem./physiol. Wirkung

Thy-1 cell surface antigen (Thy-1)/CD90 (cluster of differentiation 90) is involved in T-cell activation, neuritis outgrowth modulation, vesicular release of neurotransmitter at the synapse, astrocyte adhesion, apoptosis in carcinoma cells, tumor suppression, wound healing, fibrosis and fibrogenesis. It also controls fibroblast focal adhesion, cytoskeleton organization and cell migration.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Further mapping of an ataxia-telangiectasia locus to the chromosome 11q23 region.
Sanal O, et al.
American Journal of Human Genetics, 47(5), 860-860 (1990)
A reduction in CD90 (THY-1) expression results in increased differentiation of mesenchymal stromal cells.
Moraes DA, et al.
Stem Cell Research & Therapy, 7(1), 97-97 (2016)

Artikel

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