SAB4300587

Anti-JAK2 (Ab-570) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-JTK10 antibody produced in rabbit, Anti-Janus kinase 2 (a protein tyrosine kinase) antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.43

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~125 kDa
• Speziesreaktivität: rat, human
• Konzentration: 1 mg/mL
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• Isotyp: IgG
• Immunogene Sequenz: (G-D-Y-G-Q)
• NCBI-Hinterlegungsnummer: NP_004963.1
• UniProt-Hinterlegungsnummer: O60674
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... JAK2(3717)

Beschreibung

Allgemeine Beschreibung

JAK2 (janus kinase 2) encodes a tyrosine kinase. It belongs to the the Jak family of protein. It is located on chromosome 9p24.

Immunogen

Peptide sequence around aa. 568-572 (G-D-Y-G-Q), according to the protein JAK2.

Biochem./physiol. Wirkung

JAK2 (janus kinase 2) plays an important role in the activities of cytokines receptors. Overexpression of JAK2 results in neuroblastoma. JAK2 mutations promote primary resistance to PD-1 (anti-programmed death protein 1) blockade therapy.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Zielbeschreibung

Plays a role in leptin signaling and control of body weight.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable