N7510

Nicardipin -hydrochlorid

powder, ≥98%

• Synonym(e): 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridindicarbonsäure-methyl-{2-[methyl-(phenylmethyl)-amino]-ethyl}-ester -hydrochlorid
• Empirische Formel (Hill-System): C₂₆H₂₉N₃O₆ · HCl
• CAS-Nummer: 54527-84-3
• Molekulargewicht: 515.99
• EG-Nummer: 259-198-4
• MDL-Nummer: MFCD00057327
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24277856
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98%
• Form: powder
• Farbe: yellow
• Löslichkeit: DMSO: ~1 mg/mL; 0.1 M NaOH: insoluble; H₂O: slightly soluble; methanol: soluble
• Ersteller: EKR Therapeutics
• Lagertemp.: 2-8°C
• SMILES String: Cl[H].COC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OCCN(C)Cc3ccccc3
• InChI: 1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H
• InChIKey: AIKVCUNQWYTVTO-UHFFFAOYSA-N
• Angaben zum Gen: human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779)

Beschreibung

Biochem./physiol. Wirkung

Blocks L-type voltage-dependent calcium channels; antihypertensive.

Leistungsmerkmale und Vorteile

This compound was developed by EKR Therapeutics. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301 + H311 + H331
• P-Sätze: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges