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Merck

CACNA1S

calcium channel, voltage-dependent, L type, alpha 1S subunit

Synonyms:
CACNL1A3, CCHL1A3, Cav1.1, HOKPP, HOKPP1, MHS5, TTPP1, hypoPP
Species:
UniProtKB ID:
Gene ID:
  • Human(779) Summary: This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq, Jul 2008]
  • Mouse(12292) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • Rat(682930) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • chicken(395985) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • domestic cat(654399) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • cow(100337204) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • Horse(100034092) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • dog(490244) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • sheep(101108767) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • Domestic Rabbit(100009585) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • domestic guinea pig(100734741) calcium channel, voltage-dependent, L type, alpha 1S subunit
  • naked mole-rat(101726232) calcium channel, voltage-dependent, L type, alpha 1S subunit

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Small Molecule - Allosteric Modulator

Product Number
Description
Species
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Blocker

Product Number
Description
Species
Nicardipine hydrochloride, powder, ≥98%,
Species
human
Amlodipine besylate, ≥98% (HPLC),
Species
human
(±)-Verapamil hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Amlodipine besylate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Amlodipine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CACNA1S,
Species
human
MISSION® esiRNA, targeting mouse Cacna1s,
Species
mouse
MISSION® esiRNA, targeting mouse Cacna1e,
Species
mouse
MISSION® esiRNA, targeting human CACNA1E,
Species
human