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Wichtige Dokumente
G7504
Guanosin 3′,5′-zyklisches Monophosphat
≥98% (HPLC), powder, intracellular mediator
Synonym(e):
Cyclisches GMP, cGMP
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About This Item
Empirische Formel (Hill-System):
C10H12N5O7P
CAS-Nummer:
Molekulargewicht:
345.21
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41106305
PubChem Substanz-ID:
NACRES:
NA.77
Empfohlene Produkte
Produktbezeichnung
Guanosin 3′,5′-zyklisches Monophosphat, ≥98% (HPLC), powder
Qualitätsniveau
Assay
≥98% (HPLC)
Form
powder
Farbe
white
Löslichkeit
0.2 M NaHCO3: 50 mg/mL
Lagertemp.
−20°C
SMILES String
NC1=NC(=O)c2ncn(C3OC4COP(O)(=O)OC4C3O)c2N1
InChI
1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)
InChIKey
ZOOGRGPOEVQQDX-UHFFFAOYSA-N
Biochem./physiol. Wirkung
An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
Leistungsmerkmale und Vorteile
This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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