201030

Osmiumtetroxid

ReagentPlus^®, 99.8%

• Synonym(e): Osmium(VIII)-oxid, ‘Osmiumsäure’
• Lineare Formel: OsO₄
• CAS-Nummer: 20816-12-0
• Molekulargewicht: 254.23
• EG-Nummer: 244-058-7
• MDL-Nummer: MFCD00011150
• UNSPSC-Code: 12352303
• PubChem Substanz-ID: 329751973
• NACRES: NA.55

Eigenschaften

• Qualität: reagent
• Dampfdichte: 8.8 (vs air)
• Dampfdruck: 7 mmHg ( 20 °C)
• Produktlinie: ReagentPlus^®
• Assay: 99.8%
• Form: crystalline; powder
• Eignung der Reaktion: reagent type: oxidant
• bp: 130 °C (lit.)
• mp (Schmelzpunkt): 39.5-41 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: O=[Os](=O)(=O)=O
• InChI: 1S/4O.Os
• InChIKey: VUVGYHUDAICLFK-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Osmium tetroxide (OsO₄) is widely employed as a catalyst in various organic reactions. Stereochemical aspects of the OsO₄ assisted oxidation of allylic alcohols and their derivatives have been reported. Its reaction with olefins has been investigated. It participates as a catalyst for oxidizing fluoroquinolones, via reaction with potassium hexacyanoferrate(III) in alkaline medium. Kinetics of this oxidation reaction was studied.

Anwendung

Widely used oxidizer for visualizing cells in microscopy. Promotes oxidative cleavage of graphene layers in carbon nanotubes creating the possibility of opening ′windows′ in fullerene cages.

Osmium tetroxide may be employed as a catalyst for the hydroxylation of sterically hindered olefins.

Osmium tetroxide may be used in the following processes:

• To promote the lactonization of alkenols to lactones.
• To mediate the selective oxidative cleavage of olefins by oxone to form the corresponding ketones or carboxylic acids.
• Dihydroxylation of mono-trans-di, and trisubstituted olefins to form 1,2-diols with high enantioselectivity in the presence of chiral amines.

Rechtliche Hinweise

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H300 + H310 + H330,H314
• P-Sätze: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable