79291
4-[2-(N,N-Dimethylamino)-ethylaminosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazol
for HPLC derivatization, LiChropur™, ≥95.0% (HPLC)
Synonym(e):
7-[(2-Aminoethyl)-amino]-N-[2-(dimethylamino)-ethyl]-2,1,3-benzoxadiazol-4-sulfonamid, DAABD-AE
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Alle Fotos(2)
About This Item
Empirische Formel (Hill-System):
C12H20N6O3S
CAS-Nummer:
Molekulargewicht:
328.39
MDL-Nummer:
UNSPSC-Code:
12000000
PubChem Substanz-ID:
NACRES:
NA.22
Empfohlene Produkte
Qualität
for HPLC derivatization
LiChropur™
Qualitätsniveau
Assay
≥95.0% (HPLC)
Form
powder
Haltbarkeit
limited shelf life, expiry date on the label
Methode(n)
HPLC: suitable
Lagertemp.
2-8°C
SMILES String
CN(C)CCNS(=O)(=O)c1ccc(NCCN)c2nonc12
InChI
1S/C12H20N6O3S/c1-18(2)8-7-15-22(19,20)10-4-3-9(14-6-5-13)11-12(10)17-21-16-11/h3-4,14-15H,5-8,13H2,1-2H3
InChIKey
QKTBJERNSIEPPM-UHFFFAOYSA-N
Anwendung
4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole (DAABD-AE) is a new derivatization reagent for rapid and specific liquid chromatography tandem mass spectrometric quantification of pristanic acid, phytanic acid, and very long chain fatty acids (i.e., hexacosanoic, tetracosanoic, and docosanoic acids) in plasma.
4-[2-(N,N-Dimethylamino)ethylaminosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole may be used as derivatization reagent for the trace analysis of carboxylic acids in saliva samples using liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS).
Verpackung
Bottomless glass bottle. Contents are inside inserted fused cone.
Rechtliche Hinweise
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Yuhki Tsukamoto et al.
Biomedical chromatography : BMC, 19(10), 802-808 (2005-06-15)
The derivatization regents for carboxylic acids, DAABD-AE (4-[2-(N,N-dimethylamino)ethylaminosulfonyl]7-(2-aminoethylamino)-2,1,3-benzoxadiazole), MePZBD-AE ([4-(4-N-methyl)piperazinosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole) and APZBD-NHMe ([4-(4-N-aminoethyl)piperazinosulfonyl]-7-methylamino-2,1,3-benzoxadiazole) were developed for electrospray ionization-mass spectrometry (ESI-MS). The derivatization reaction with fatty acids was completed at 60 degrees C within 30 min. The derivatives of fatty acids
Tatsuya Higashi et al.
Journal of pharmaceutical and biomedical analysis, 52(5), 809-818 (2010-04-09)
A simple and practical derivatization procedure for increasing the detection responses of carboxylic acids in liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) has been developed. 2-Hydrazinopyridine (HP) and 2-picolylamine (PA) rapidly reacted with biologically and clinically important carboxylic acids [chenodeoxycholic acid
Osama Y Al-Dirbashi et al.
Journal of lipid research, 49(8), 1855-1862 (2008-04-29)
Quantification of pristanic acid, phytanic acid, and very long chain fatty acids (i.e., hexacosanoic, tetracosanoic, and docosanoic acids) in plasma is the primary method for investigateing a multitude of peroxisomal disorders (PDs). Typically based on GC-MS, existing methods are time-consuming
Milene Volpato et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1055-1056, 125-134 (2017-05-04)
As pre-clinical and clinical research interest in ω-3 polyunsaturated fatty acids (PUFA) increases, so does the need for a fast, accurate and reproducible analytical method to measure fatty acids (FA) in biological samples in order to validate potential prognostic and
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