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Merck

89803

Supelco

O-Methylhydroxylamin -hydrochlorid

for GC derivatization, LiChropur, 97.5-102.5% (AT)

Synonym(e):

Methoxyamin -hydrochlorid, Methoxylamin -hydrochlorid

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About This Item

Lineare Formel:
CH3ONH2 · HCl
CAS-Nummer:
Molekulargewicht:
83.52
Beilstein:
3589723
MDL-Nummer:
UNSPSC-Code:
41116105
NACRES:
NA.05

Qualität

for GC derivatization
LiChropur

Qualitätsniveau

Assay

97.5-102.5% (AT)

Form

crystals

Eignung der Reaktion

reagent type: derivatization reagent
reaction type: Acylations

Methode(n)

gas chromatography (GC): suitable

mp (Schmelzpunkt)

151-154 °C (lit.)

SMILES String

Cl.CON

InChI

1S/CH5NO.ClH/c1-3-2;/h2H2,1H3;1H

InChIKey

XNXVOSBNFZWHBV-UHFFFAOYSA-N

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Allgemeine Beschreibung

Methoxyamine hydrochloride is a commonly used reagent for the generation of oxime derivatives of aldehyde- or ketone-group containing compounds. It is typically employed as an oximation reagent prior to silylation derivatizations.

Anwendung

Methoxyamine hydrochloride can be used as:
  • A reagent for the preparation of O-methyl oximes.
  • A reagent used to make O-methyl oximes from aldehydes or ketones.
  • An alkylation reagent.
  • It may be used as a derivatization agent to improve the sensitivity of opioids, steroids and ionic metabolites in biological samples and non-volatile flavor compounds in "Angeleno" plum fruit prior to the determination of analytes using gas chromatography-mass spectrometry (GC-MS) technique.

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Rechtliche Hinweise

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Design of experiments: an efficient strategy to identify factors influencing extraction and derivatization of Arabidopsis thaliana samples in metabolomic studies with gas chromatography/mass spectrometry.
Gullberg J, et al.
Analytical Biochemistry, 331(2), 283-295 (2004)
Data correction strategy for metabolomics analysis using gas chromatography-mass spectrometry.
Kanani HH and Klapa MI
Metabolic engineering, 9(1), 39-51 (2007)

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