45706

Warfarin

PESTANAL^®, analytical standard

• Synonym(e): 4-Hydroxy-3-(3-oxo-1-phenylbutyl)-cumarin, Coumafen
• Empirische Formel (Hill-System): C₁₉H₁₆O₄
• CAS-Nummer: 81-81-2
• Molekulargewicht: 308.33
• Beilstein: 8868198
• EG-Nummer: 201-377-6
• MDL-Nummer: MFCD00006854
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329756915
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Produktlinie: PESTANAL^®
• Haltbarkeit: limited shelf life, expiry date on the label
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• mp (Schmelzpunkt): 162-164 °C (lit.)
• Anwendung(en): agriculture; environmental
• Format: neat
• SMILES String: CC(=O)CC(c1ccccc1)C2=C(O)c3ccccc3OC2=O
• InChI: 1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3
• InChIKey: PJVWKTKQMONHTI-UHFFFAOYSA-N
• Angaben zum Gen: human ... VKORC1(79001)

Beschreibung

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Warfarin is an anticoagulant commonly used in the prevention of thrombosis and thromboembolism. Its use is studied in stroke and pulmonary fibrosis patients among many others. It is used to study potential risks and interactions with other drugs and food.

Biochem./physiol. Wirkung

Warfarin consists of a racemic mixture of two active enantiomers, R- and S- forms. Warfarin is slower-acting than the common anticoagulant heparin. Warfarin inhibits the vitamin K-dependent synthesis of biologically active forms of the calcium-dependent clotting factors II, VII, IX and X. It inhibits regulatory factors protein C, protein S, and protein Z.

Vorsicht

Nur für den berufsmässigen Verwender.Achtung − Kontakt vermeiden −. Vor Gebrauch besondere Anweisungen einholen.

Rechtliche Hinweise

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H300 + H310 + H330,H360D,H372,H411
• P-Sätze: P202 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Gefahreneinstufungen: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Repr. 1A - STOT RE 1 Oral
• Zielorgane: Blood
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3