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04936

Sigma-Aldrich

O-(6-Chlorbenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium-hexafluorphosphat

≥98.0% (HPLC)

Synonym(e):

1-[Bis-(dimethylamino)-methylen]-5-chlor-benzotriazolium-3-oxid-hexafluorophosphat, N,N,N′,N′-Tetramethyl-O-(6-chlor-1H-benzotriazol-1-yl)-uronium-hexafluorphosphat, HCTU

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About This Item

Empirische Formel (Hill-System):
C11H15ClF6N5OP
CAS-Nummer:
330645-87-9
Molekulargewicht:
413.69
MDL-Nummer:
MFCD04973268
UNSPSC-Code:
12352101
PubChem Substanz-ID:
329747994
NACRES:
NA.22

Qualitätsniveau

200

Assay

≥98.0% (HPLC)

Form

powder

Eignung der Reaktion

reaction type: Coupling Reactions

Verunreinigungen

≤0.5% water

mp (Schmelzpunkt)

185-190 °C

Anwendung(en)

peptide synthesis

SMILES String

ClC1=CC=C(N([C+](N(C)C)N(C)C)N=[N+]2[O-])C2=C1.F[P-](F)(F)(F)(F)F

InChI

1S/C11H15ClN5O.F6P/c1-15(2)11(16(3)4)18-17-10-7-8(12)5-6-9(10)13-14-17;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1

InChIKey

ZHHGTMQHUWDEJF-UHFFFAOYSA-N

Verwandte Kategorien

Anwendung

Reagent for:
Synthesis of near-infrared pH activatable fluorescent probes
Synthesis of human β-amyloid by Fmoc chemistry
Stereoselective Horner-Wadsworth-Emmons olefination
Covalent ligation of fluorescent peptides to quantum dots
Alkylation of human telomere sequence

Sonstige Hinweise

Tandem Oligonucleotide Synthesis on Solid-Phase Supports for the Production of Multiple Oligonucleotides

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H317

Gefahreneinstufungen

Skin Sens. 1A

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
BCCD7640
BCBZ3421
BCBT4008
BCBR0407V
BCBQ8232V

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Hyeran Lee et al.
Bioconjugate chemistry, 22(4), 777-784 (2011-03-11)
Highly tumor selective near-infrared (NIR) pH-activatable probe was developed by conjugating pH-sensitive cyanine dye to a cyclic arginine-glycine-aspartic acid (cRGD) peptide targeting α(v)β(3) integrin (ABIR), a protein that is highly overexpressed in endothelial cells during tumor angiogenesis. The NIR pH-sensitive
Fast conventional synthesis of human beta-amyloid (1-42) on the Symphony and Prelude.
German Fuentes et al.
Advances in experimental medicine and biology, 611, 173-174 (2009-04-30)
Amit Kumar Tripathi et al.
Scientific reports, 7(1), 3384-3384 (2017-06-15)
Marine fish antimicrobial peptide, chrysophsin-1 possesses versatile biological activities but its non-selective nature restricts its therapeutic possibilities. Often small alterations in structural motifs result in significant changes in the properties of concerned proteins/peptides. We have identified GXXXXG motif in chrysophsin-1.
Wouter A van der Linden et al.
Organic & biomolecular chemistry, 8(8), 1885-1893 (2010-05-08)
The synthesis and biological evaluation of ten Michael acceptors containing potential proteasome inhibitors are described. Cellular targets of azide containing inhibitors and were assessed in HEK293T and RAW264.7 cells by a two step labeling strategy, followed by biotin-pulldown, affinity purification
Richard T Pon et al.
The Journal of organic chemistry, 67(3), 856-864 (2002-02-22)
More than one oligonucleotide can be synthesized at a time by linking multiple oligonucleotides end-to-end in a tandem manner on the surface of a solid-phase support. The 5'-terminal hydroxyl position of one oligonucleotide serves as the starting point for the
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