EZGLP2

Rat/Human GLP-2 ELISA Kit

detects GLP-2 in 50 μL serum, plasma or cell culture supernatent

• Synonym(e): Glucagon-like peptide-2
• UNSPSC-Code: 12161503
• eCl@ss: 32161000
• NACRES: NA.32

Eigenschaften

• product name: GLP-2 ELISA, This GLP-2 ELISA is used to measure & quantify GLP-2 levels in Metabolism & Endocrine research.
• Qualitätsniveau: 200
• Speziesreaktivität: human, rat
• Verpackung: kit of 1 × 96 wells
• Parameter: 50 μL sample volume (4hr assay)
• assay range: accuracy: 75-97%; (Human); accuracy: 94-109%; (Rat); sensitivity: 1 ng/mL; (50 μl sample size); standard curve range: 1-64 ng/mL; inter-assay cv: <12%; intra-assay cv: <10%
• Methode(n): ELISA: suitable
• Aufnahme: sample type plasma (K2 EDTA); sample type serum
• Anwendung(en): research use
• Nachweisverfahren: colorimetric (450nm/590nm)
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

The glucagon-like peptides GLP-1 and GLP-2 are important gut hormones released from the small intestine upon nutrient ingestion. In circulation, GLP-2 is present in two molecular forms, GLP-2 (1-33) and GLP-2 (3-33). Similar to GLP-1, active form GLP-2 (1-33) is cleaved to inactive form GLP-2 (3-33) by protease DPPIV. GLP-2 has been shown to play important roles in the regulation of gastrointestinal functions (digestion, absorption, motility, epithelial growth, and blood flow) and bone resorption. Thus, GLP-2 or its analogs may have therapeutic potentials for the treatment of diseases such as Crohn’s disease and osteoporosis.

Spezifität

Human GLP-2 1-33 100%
Human GLP-2 3-33 112%
Rat GLP-2 101%

Anwendung

Research Category
Stoffwechsel

Research Sub Category
Osteoporosis

This assay requires 50 µl of rat or human samples and is performed at room temperature as a 4 hour assay. GLP-2 has also been detected in guinea pig, horse, porcine, and non-human primate samples.

Used to detect/quantify: GLP-2

Sonstige Hinweise

Please contact Technical Service for linearity of dilution.

Haftungsausschluss

For research use only. Not for use in diagnostic procedures.

Sicherheitshinweise

• Piktogramme: GHS06,GHS05,GHS09
• Signalwort: Danger
• H-Sätze: H290,H302 + H332,H311,H317,H319,H335,H411
• P-Sätze: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects