8.51029

N-Biotinyl-NH-(PEG)₂-COOH . DIPEA (20 atoms)

Novabiochem^®

• Synonym(e): O-(N-Biotinyl-3-aminopropyl)-O′-(N-glutaryl-3-aminopropyl)-diethyleneglycol · DIPEA
• Empirische Formel (Hill-System): C₂₅H₄₄N₄O₈S · xC₈H₁₉N
• CAS-Nummer: 1205744-09-7
• Molekulargewicht: 560.70
• UNSPSC-Code: 12352106
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Produktlinie: Novabiochem^®
• Assay: ≥95.0% (HPLC); ≥98% (TLC)
• Form: powder
• Eignung der Reaktion: reaction type: Biotinylations
• Hersteller/Markenname: Novabiochem^®
• mp (Schmelzpunkt): 131-136 °C
• Anwendung(en): peptide synthesis
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

The use of this novel biotin derivative incorporates a hydrophilic 20 atom PEG spacer between the peptide and biotin. This not only greatly improves the solubility of the resultant peptide, but reduces steric hindrance between the peptide and biotin, leading to better avidin binding and higher biological activity. The biotin-PEG derivative can be easily incorporated using any standard coupling method as the final step in SPPS, immediately prior to cleavage of the peptide from the resin.

Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis

Verlinkung

Replaces: 01-63-0133

Hinweis zur Analyse

Farbe (visuell): weiß bis schwach gelb bis beige
Aussehen der Substanz (visuell): Pulver
Identität (IR): entspricht
Reinheit (DC(CMA2)): ≥ 98 %
Gehalt (HPLC, Fl.%): ≥ 95.0 % (a/a)
Löslichkeit (50 mg in 1 ml NMP): klar löslich
DC-Bedingungen gemäß den Angaben unseres Hauptkataloges

Rechtliche Hinweise

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable