495417-M

N-Oleoyl Ethanolamine

A potent inhibitor of the ceramidase found in human kidney and cerebellum.

• Synonym(e): N-Oleoyl Ethanolamine, N-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA
• Empirische Formel (Hill-System): C₂₀H₃₉NO₂
• CAS-Nummer: 111-58-0
• Molekulargewicht: 325.53
• MDL-Nummer: MFCD00045972
• UNSPSC-Code: 12352211

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (TLC)
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze
• Farbe: white
• Löslichkeit: chloroform: 5 mg/mL; ethanol: 5 mg/mL; methanol: 5 mg/mL
• Lagertemp.: −20°C
• InChI: 1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
• InChIKey: BOWVQLFMWHZBEF-KTKRTIGZSA-N

Beschreibung

Allgemeine Beschreibung

A potent inhibitor of the ceramidase found in human kidney and cerebellum. A specific inhibitor of acid ceramidase (IC₅₀ ~ 500 µM).

A potent inhibitor of the ceramidase found in human kidney and cerebellum. Blocks the conversion of ceramide to sphingosine. A specific inhibitor of acid ceramidase (IC₅₀ ~ 500 µM).

Biochem./physiol. Wirkung

Primary Target
Acid ceramidase

Target IC₅₀: ~ 500 µM against acid ceramidase

Warnhinweis

Toxicity: Standard Handling (A)

Sonstige Hinweise

Pahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
Sugita, M., et al. 1975. Biochim. Biophys. Acta398, 125.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable