810211C

C12-NBD Ceramide

Avanti Research^™ - A Croda Brand 810211C

• Synonym(e): N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-erythro-sphingosine
• Empirische Formel (Hill-System): C₃₆H₆₁N₅O₆
• CAS-Nummer: 202850-01-9
• Molekulargewicht: 659.90
• MDL-Nummer: MFCD02259239
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: liquid
• Verpackung: pkg of 1 × 1 mL (810211C-1mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 810211C
• Konzentration: 1 mg/mL (810211C-1mg)
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [N+](=O)([O-])c1c2n[o]nc2c(cc1)NCCCCCCCCCCCC(=O)N[C@H]([C@H](O)\C=C\CCCCCCCCCCCCC)CO
• InChI: 1S/C36H61N5O6/c1-2-3-4-5-6-7-8-9-10-12-15-18-21-24-33(43)31(29-42)38-34(44)25-22-19-16-13-11-14-17-20-23-28-37-30-26-27-32(41(45)46)36-35(30)39-47-40-36/h21,24,26-27,31,33,37,42-43H,2-20,22-23,25,28-29H2,1H3,(H,38,44)/b24-21+/t31-,33+/m0/s1
• InChIKey: SNOJCYCOPNIGIK-ULETYAGTSA-N

Beschreibung

Anwendung

C12-NBD ceramide is suitable for its use:

• as a substrate to measure the activity of acid, alkaline and neutral ceramidases
• in in vitro ceramidase activity assay
• in ceramide phosphoethanolamine (CPE) synthase assay to determine the K_m and V_max of sphingomyelin synthase (SMS1, SMS2, and SMSr)

Biochem./physiol. Wirkung

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthase family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

Verpackung

5 mL Amber Glass Screw Cap Vial (810211C-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H302,H315,H319,H331,H336,H351,H361d,H372
• P-Sätze: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Zielorgane: Central nervous system
• WGK: WGK 3