700051P

22(S)-hydroxycholesterol-d7

Avanti Research^™ - A Croda Brand

• Synonym(e): 25,26,26,26,27,27,27-heptadeuterocholest-5-ene-3β,22S-diol
• Empirische Formel (Hill-System): C₂₇H₃₉O₂D₇
• CAS-Nummer: 1246302-91-9
• Molekulargewicht: 409.70
• MDL-Nummer: MFCD00079091
• UNSPSC-Code: 41141804
• NACRES: NA.25

Eigenschaften

• Beschreibung: cholest-5-ene-3β,22(S)-diol-d7
• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 1 mg (700051P-1mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand
• Versandbedingung: dry ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

22(S)-hydroxycholesterol is an enantiomer of 22(R)-hydroxycholesterol. 22(S)-hydroxycholesterol-d7 is a deuterated form of 22(S)-hydroxycholesterol.

Anwendung

22(S)-hydroxycholesterol-d7 may be used as an internal standard in liquid chromatography with tandem mass spectrometry (LC-MS-MS) analysis of plasma low-density lipoprotein (LDL).

Biochem./physiol. Wirkung

22(S)-hydroxycholesterol (22(S)-HC) promotes glucose catabolism and uptake and is regarded as a potential target to treat type 2 diabetes. 22(S)-HC also prevents the accumulation of lipids and lipid synthesis in hepatocytes and myotubes. Unlike 22(R)-hydroxycholesterol, 22(S)-HC is not estrogenic and is not a ligand for liver X receptor (LXR).

Verpackung

5 mL Amber Glass Screw Cap Vial (700051P-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids