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Merck

920819

Sigma-Aldrich

mPEG functionalized alginate

5% +/- 2% PEGylation, PEG average Mn 1k

Synonym(e):

PEGylated alginate, PEGylated low viscosity alginate, PEGylated sodium alginate

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About This Item

Lineare Formel:
{C6H7O5[NHCH2CH2CH2O(CH2CH2O)xCH3]}n(C6H7O6Na)m
UNSPSC-Code:
12352201
NACRES:
NA.23

Qualitätsniveau

Form

(solid or chunk(s) or fiber)

Mol-Gew.

PEG average Mn 1k

Farbe

white to off-white

Lagertemp.

2-8°C

Anwendung

Alginate is biocompatible and biodegradable, and forms hydrogels in the presence of divalent cations (e.g., Ca2+, Ba2+) under mild temperature and pH conditions. mPEG functionalized alginate can used to tune the stress relaxation of alginate hydrogels, and can used to fabricate microparticles with better mechanical properties.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Varying PEG density to control stress relaxation in alginate-PEG hydrogels for 3D cell culture studies
Nam S., et al.
Biomaterials, 200, 15-24 (2019)
Solène Passemard et al.
Biomacromolecules, 18(9), 2747-2755 (2017-07-26)
The production of hydrogel microspheres (MS) for cell immobilization, maintaining the favorable properties of alginate gels but presenting enhanced performance in terms of in vivo durability and physical properties, is desirable to extend the therapeutic potential of cell transplantation. A
Xu Jia et al.
ACS biomaterials science & engineering, 2(9), 1641-1648 (2016-09-12)
Theranostic nanomedicine has recently emerged as an appealing approach for tumor chemotherapy. Here, for the first time, fluorescent carbon dots (Cdots) were used as cross-linker for tumor theranostic nanoparticles. Novel theranostic nanoparticles of approximately 27 nm with a doxorubicin (DOX)
Redouan Mahou et al.
Materials (Basel, Switzerland), 7(1), 275-286 (2014-01-09)
The progress of medical therapies, which rely on the transplantation of microencapsulated living cells, depends on the quality of the encapsulating material. Such material has to be biocompatible, and the microencapsulation process must be simple and not harm the cells.
Sungmin Nam et al.
Biomaterials, 200, 15-24 (2019-02-12)
Hydrogels are commonly used as artificial extracellular matrices for 3D cell culture and for tissue engineering. Viscoelastic hydrogels with tunable stress relaxation have recently been developed, and stress relaxation in the hydrogels has been found to play a key role

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