795569

Garg 4,5-indolyne precursor

95%

• Synonym(e): 4-(Trimethylsilyl)-1H-indol-5-yl trifluoromethanesulfonate
• Empirische Formel (Hill-System): C₁₂H₁₄F₃NO₃SSi
• CAS-Nummer: 1259448-37-7
• Molekulargewicht: 337.39
• MDL-Nummer: MFCD25976536
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 329768491
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: solid
• mp (Schmelzpunkt): 43-48 °C
• Funktionelle Gruppe: fluoro; triflate
• Lagertemp.: 2-8°C
• SMILES String: O=S(OC1=C([Si](C)(C)C)C2=C(NC=C2)C=C1)(C(F)(F)F)=O
• InChI: 1S/C12H14F3NO3SSi/c1-21(2,3)11-8-6-7-16-9(8)4-5-10(11)19-20(17,18)12(13,14)15/h4-7,16H,1-3H3
• InChIKey: LLCJFYYASDIOJN-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Garg 4,5-indolyne precursor is an indolyne precursor developed by Professor Neil Garg and coworkers. It is widely used for the synthesis of various N-heterocyclic based compounds. It is also useful for the preparation of substituted indoles (Diels–Alder and azide cycloaddition products).

Anwendung

Indolyne precursor can be activated under mild fluoride conditions, which are highly reactive with dienes and other dipolariphiles (e.g. azides) to provide cycloaddition products containing an indole motif.

Sonstige Hinweise

Indolyne Experimental and Computational Studies: Synthetic Applications and Origins of Selectivities of Nucleophilic Additions

Regioselective reactions of 3; 4-pyridynes enabled by the aryne distortion model

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable