718831

4-(Carboxymethyl)phenyl-Boronsäurepinakolester

95%

• Synonym(e): 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-phenylessigsäure, Phenylessigsäure-4-boronsäure-pinakolester
• Empirische Formel (Hill-System): C₁₄H₁₉BO₄
• CAS-Nummer: 797755-07-8
• Molekulargewicht: 262.11
• MDL-Nummer: MFCD04038755
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 329763612
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: solid
• mp (Schmelzpunkt): 165-170 °C
• SMILES String: CC1(C)OB(OC1(C)C)c2ccc(CC(O)=O)cc2
• InChI: 1S/C14H19BO4/c1-13(2)14(3,4)19-15(18-13)11-7-5-10(6-8-11)9-12(16)17/h5-8H,9H2,1-4H3,(H,16,17)
• InChIKey: FNLWHBHWDXCWHV-UHFFFAOYSA-N

Beschreibung

Anwendung

4-(Carboxymethyl)phenylboronic acid pinacol ester can be used:

• As an intermediate to prepare hydantoin-derived autotaxin inhibitors.
• As a substrate in the synthesis of reactive oxygen species (ROS)-sensitive and H₂O₂-eliminating materials by interlinking phenylboronic acid pinacol esters onto β-cyclodextrin.
• To prepare 5-aryl-2-aminopyridine derived FLT3 kinase inhibitors.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable