643777

Di-tert-butyl(methyl)phosphoniumtetrafluoroborat

97%

• Synonym(e): (t-Bu)2PMeHBF4, Bis(1,1-dimethylethyl)methylphosphine tetrafluoroborate
• Empirische Formel (Hill-System): C₉H₂₂BF₄P
• CAS-Nummer: 479094-62-7
• Molekulargewicht: 248.05
• MDL-Nummer: MFCD03840579
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 24883295
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: solid
• Eignung der Reaktion: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand; reaction type: Cross Couplings
• pH-Wert: 1.79 (1% in solution)
• mp (Schmelzpunkt): >230 °C (lit.)
• Funktionelle Gruppe: phosphine
• SMILES String: F[B-](F)(F)F.C[PH+](C(C)(C)C)C(C)(C)C
• InChI: 1S/C9H21P.BF4/c1-8(2,3)10(7)9(4,5)6;2-1(3,4)5/h1-7H3;/q;-1/p+1
• InChIKey: BRDLRXCAHKUWJS-UHFFFAOYSA-O

Beschreibung

Anwendung

Di-tert-butyl(methyl)phosphonium tetrafluoroborate may be used in the preparation of a precursor for nantenine analogs bearing a C4 phenyl substituent, which shows an affinity for 5-HT_2B receptor. It may also be used in the palladium-catalyzed borylation of primary alkyl electrophiles (bromides, iodides or tosylates) using bis(pinacolato)diboron or bis(neopentyl glycolato)diboron as the boron source.

The phosphonium salt is used for Pd catalyzed cross coupling reaction.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310
• Gefahreneinstufungen: Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges