559210

Ethyl-(4-chlorbenzoyl)acetat

• Synonym(e): 3-(4-Chlorophenyl)-3-oxopropanoic acid ethyl ester, Ethyl 3-(4-chlorophenyl)-3-oxopropanoate, NSC 406743
• Lineare Formel: ClC₆H₄COCH₂CO₂C₂H₅
• CAS-Nummer: 2881-63-2
• Molekulargewicht: 226.66
• MDL-Nummer: MFCD00018713
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24879805
• NACRES: NA.22

Eigenschaften

• Form: solid
• Qualitätsniveau: 100
• Brechungsindex: n20/D 1.5500 (lit.)
• bp: 268-269 °C (lit.)
• Dichte: 1.218 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: chloro; ester; ketone
• SMILES String: CCOC(=O)CC(=O)c1ccc(Cl)cc1
• InChI: 1S/C11H11ClO3/c1-2-15-11(14)7-10(13)8-3-5-9(12)6-4-8/h3-6H,2,7H2,1H3
• InChIKey: DGCZHKABHPDNCC-UHFFFAOYSA-N

Beschreibung

Anwendung

Ethyl (4-chlorobenzoyl)acetate may be used to synthesize 2-(carboethoxy)-3-(4′-chloro)phenylquinoxaline 1,4-dioxide.

Reactant involved in:

• Tandem condensation-cyclization reactions
• Stereoselective ketonization-olefination of indoles
• Synthesis of antiplasmodial agents
• SIRT 1/2 inhibitor preparation for use as antitumor agents
• Synthesis of mineralocorticoid receptor antagonists
• Intramolecular Michael addition reactions

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)