480142

4-Phenoxyphenylborsäure

≥95.0%

• Lineare Formel: C₆H₅OC₆H₄B(OH)₂
• CAS-Nummer: 51067-38-0
• Molekulargewicht: 214.02
• MDL-Nummer: MFCD00093312
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24871550
• NACRES: NA.22

Eigenschaften

• Assay: ≥95.0%
• mp (Schmelzpunkt): 141-145 °C (lit.)
• Funktionelle Gruppe: phenoxy
• SMILES String: OB(O)c1ccc(Oc2ccccc2)cc1
• InChI: 1S/C12H11BO3/c14-13(15)10-6-8-12(9-7-10)16-11-4-2-1-3-5-11/h1-9,14-15H
• InChIKey: KFXUHRXGLWUOJT-UHFFFAOYSA-N

Beschreibung

Anwendung

4-Phenoxyphenylboronic acid can be used as a reactant:

• In the Suzuki-Miyaura coupling reaction to synthesize aryl derivatives via C-C bond formation by reacting with different aryl halides over a palladium catalyst.
• To prepare 1-phenoxy-4-(trifluoromethyl)benzene via oxidative trifluoromethylation using Chan-Lam-type reaction conditions.
• To synthesize evobrutinib, a potent Bruton′s tyrosine kinase (BTK) inhibitor.

Sonstige Hinweise

Contains varying amounts of anhydride

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)