39933

(S)-4-Isopropylthiazolidin-2-thion

≥98.0%

• Empirische Formel (Hill-System): C₆H₁₁NS₂
• CAS-Nummer: 76186-04-4
• Molekulargewicht: 161.29
• MDL-Nummer: MFCD03844797
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 57649913
• NACRES: NA.22

Eigenschaften

• Assay: ≥98.0%
• Form: solid
• Optische Aktivität: [α]20/D -37±3°, c = 1 in chloroform
• Optische Reinheit: ee: ≥99:1 (LC)
• mp (Schmelzpunkt): 69-71 °C
• SMILES String: CC(C)[C@H]1CSC(=S)N1
• InChI: 1S/C6H11NS2/c1-4(2)5-3-9-6(8)7-5/h4-5H,3H2,1-2H3,(H,7,8)/t5-/m1/s1
• InChIKey: CWIZUGZKLJDJLE-RXMQYKEDSA-N

Beschreibung

Anwendung

A highly selective and efficient chiral auxiliary which can be directly reduced to its corresponding aldehyde and the chiral auxiliary by reductive cleavage with diisobutylaluminum hydride.

(S)-4-Isopropylthiazolidine-2-thione may be used as a chiral auxiliary for the stereochemical induction at the phosphorus atom during the diastereoselective synthesis of aryloxy phosphoramidate prodrugs of 3′-deoxy-2′,3′-didehydrothymidine monophosphate (d4TMP).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)